Pseudopseudohypoparathyroidism

That is a real word.  Pseudopseudohypoparathyroidism.  It’s an eyeful but fun to say out loud three times.  Did you know there are about 17,000 different thyroid conditions out there?  There is hypothyroidism, euthyroidism, hyperthyroidism, autoimmune thyroiditis, thyroid resistance, and all sorts of parathyroid problems.  The ones that seem to concern fibromyalgia patients are:

  1. Hypothyroidism: essentially having discernable low levels of thyroid which can then be treated by boosting the levels.  The symptoms between hypothyroidism and fibromyalgia are very similar.
  2. Euthyroidism: essentially having normal levels of thyroid.  That whole “within normal limits” thing.
  3. Autoimmune thyroiditis: when the body decides thyroid is actually a threat and releases antibodies which destroys thyroid.  This is genetically passed on.  The antibodies can be tested for, and there is a fairly high percentage of fibro patients who test positive for the antibodies.
  4. Thyroid resistance: essentially, there’s plenty of thyroid hormone, but the body doesn’t know what to do with it, also called “impaired sensitivity to thyroid hormone.”  Again, there have been studies which indicate a fairly high prevalence of this in fibro patients.

I haven’t been able to find (yet) a solid discussion of the consequences of untreated abnormalities like autoimmune thyroiditis and thyroid resistance, but it is possible (according to Garrison et al) to have “multiple hormone resistances,” and to fix one hormone resistance (like thyroid resistance) can cause a cascade effect on other out-of-balance hormones.  Since there are so MANY hormones and chemicals out of balance in fibro patients (yeah, yeah, I haven’t gotten the chart on line yet), I don’t quite understand the reluctance to continue this line of inquiry.  It’s kind of bothering me, so onward I trudge trying to find someone looking at this line of thought.  Besides me.

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